Graph spectral analysis of protein interaction network evolution
نویسندگان
چکیده
منابع مشابه
Graph spectral analysis of protein interaction network evolution
We present an analysis of protein interaction network data via the comparison of models of network evolution to the observed data. We take a bayesian approach and perform posterior density estimation using an approximate bayesian computation with sequential Monte Carlo method. Our approach allows us to perform model selection over a selection of potential network growth models. The methodology ...
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Proteins are linear polymers built from 20 building blocks called amino acids. Parts of a protein that are found conserved in many other proteins are called domains; these domains are usually responsible for the protein-protein interactions. Protein-protein interactions (PPIs) are transient or permanent connections between proteins, and they are important for many biological phenomena such as s...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2012
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2012.0220